What form of audience do social tags of this kind enable Discuss the Essay

What form of audience do social tags of this kind enable Discuss the social and communicative properties of this kind of audience, using these tweets as evidence to support your claims - Essay Example Social tagging also plays a major role in connecting the users who have similar interests. The users can be able to share among themselves relevant piece of information regarding their area of interest (OReilly, & Milstein, 2009). Different tweets are usually posted to address different types of audiences. The different types of audiences have a common characteristic in that they are all imaginary in the mind of the writer. The three main types of audiences to which tweets can be addressed include (Clark 2012); the writer’s audience, the networked audience, and the broadcast audience. The writer’s audience: In this type of audience, the user tries to imagine the potential audience that have a high likelihood of gaining interest in the intended tweet and composes the tweet that is tailored for the perceived audience. The user tries to form a picture of the audience in his/her mind in order to compose a tweet that will meet the needs of that specified group of audience. The user usually expects responses from the audience. The broadcast audience: In type of audience, the user does not have a specific group of audiences in mind. The user just composes a tweet that is intended for any audience. For this situation, the user does not expect to get any response regarding the tweet. They compose a tweet that is meant for the consumption of the general public, and response for them is not a priority. The networked audience: This type of audience combines the characteristics of both the writer and the broadcast audience. Unlike in the broadcast audience, the user here composes a tweet that is intended of a large group of audience, but he/she has an idea of the type of audience to which the tweet is intended for. Just like in the writer’s audience, the user here also expects to get responses from the audience regarding the tweet. According to the sample tweets that have been provided, the form of audience that is most likely to be enable is the

Health promotion initiative Essay Example | Topics and Well Written Essays - 2500 words

Health promotion initiative - Essay Example It should be noted that the area is crime prone and incidences of drug abuse are very common. According to records, a portion of the population shared needles from intravenous drug use and there is widespread homosexual promiscuity. In the 1990s, the Belle Glade community had the highest HIV/AIDS prevalence rate in the United States. The AIDS scourge is widespread in the entire area cutting across all the major demographics of Hispanics and Black Americans. One of the reasons for the high AIDS prevalence rate is the sharing of needles used in intravenous drug injections. The high risk people include drug users who are also engaged in promiscuity. Lack of knowledge and information about AIDS contributes to the high prevalence rates in the region especially among the gay people. These high risk people are not equipped with the right information on AIDS and therefore inadvertently put themselves and the entire community at a high risk of infection. It is therefore important to undertake a health promotion initiative in Belle Glade community so as to curb the issue of HIV/AIDS. Notably, measures have to be put in place to ensure that new infection cases are eliminated and those that are infected get the right information to live in a healthy manner. It is also important to note that the use of drugs and high rates of promiscuity play a major role in the spread of HIV/AIDS in the Belle Glade community. Therefore, the health promotion is intended to cover the whole spectrum of HIV/AIDS spread and infection management. According to the Ottawa Charter (1986), health promotion is based on the social ecological factors that determine the health of the society. Health promotion initiatives aim at mobilizing resources for good health. It should be noted that health promotion is salute-genetic and it involves a multi sectoral approach. Based on the Ottawa

Neurotransmitter and Hormone Receptors

Neurotransmitter and Hormone Receptors 1) Transcription of DNA and translation into protein are tightly regulated in Eukaryota cells. Give an account of the key steps involved. Gene expression is under continuous regulation. This regulation is differentiated between Eukaryotic and Prokaryotic organisms, especially due to matters of complexity. In Prokaryotic organisms the regulation of gene expression is happening only at the stage of transcription and includes one stage. On the other hand, the regulation of gene expression in Eukaryotic organisms is happening not only in transcriptional level, but also at post-transcriptional, translation and post-translation level (Latchman 2007). The figure on the right shows the steps of gene expression that can be regulated. In case where the regulation of gene expression happens in transcriptional level, then the levels of cytoplasmic mRNA and nuclear RNA should be paralleled. On the other hand, in case a gene is being transcribed in the same manner in all tissues, there will be a difference in the majority of tissues between the cytoplasm mRNA and RNA, due to post-transcriptional mechanisms. As a result, in order to distinguish post-transcriptional and transcriptional regulation the first approach is to see if there are changes between the RNA levels in the tissues (Latchman 2007). Initiation of transcription In many cases where there is an increased level of transcription, this results from a high level of transcriptional initiation mediated by RNA polymerase responsible for initiating the process. This means that in a tissue that occurs an active transcription process, the RNA polymerases will be moving beside the gene continuously, and thus increasing the rate of transcript production. In contrast, in tissues where a gene is transcribed at low levels, the initiation of transcription will not be so apparent and the level of transcripts will be significantly low (Latchman 2007). Elongation Except of the initiation of transcription which seems to occur in the majority of the cases, there has been demonstrated that the regulation can also happen during at a post-initiation level by producing a shortened RNA than the full length one. In this case, the transcriptional control seems to happen by blocking the elongation of a newly formed transcript (Latchman 2007). DNA elements The expression of protein-coding genes is regulated also by specific DNA elements, which are located usually upstream of the initiation site of the gene. These DNA elements can influence positively or negatively the transcription of a gene. For example, DNA sequences such as insulators and silencers, suppress the genes transcription (Latchman 2007). Transcription Factors The transcription factors are also important modulatory elements of transcription. The binding of specific transcription factors on the DNA, can either activate or suppress gene transcription (Latchman 2007) . Although so far we discussed the transcriptional control of gene expression, which corresponds to the most abundant transcriptional control mechanism, there have been cases where even though the transcription rate of a gene doesnt change, changes in the synthesis of specific proteins have occurred. This control mechanism occurs between the translational and transcription control and includes splicing of the nascent mRNA, alternative splicing, and regulation of RNA stability. The splicing of the RNA is the process in which the protein coding regions are encoded by exons, after removing the intervening sequences which are named introns (Latchman 2007). The alternative splicing, includes the differentiated processing of RNAs in order to produce different RNA variants (Black 2000). The translational control of gene expression, corresponds to mRNA regulation and is also a very important regulatory stage. In the same manner as transcriptional control, translation can be affected either positively or negatively by altering the levels of specific translation factors, and most of the times it happens at the initiation of the translation process due to differences in the 5 untranslated region of the mRNA. During translation, the 5 un-translated region contains an AUG triplet of bases which is important to be located in a favorable context. This means, that if the ribosome is incapable of recognizing this triplet, then the initiation of translation is inhibited. For example, in a situation which is called leaky scanning, when AUG codons are located upstream, the ribosome has a difficulty to recognize them (Wickens et al. 2000). Furthermore, except of the recognition of the AUG codon, other coding regions seem to play an important regulatory role. For example, some frequencies which are located in the open reading frame of the mRNA (ORF) seem to cause a frameshift at a specific triplet both in viral and mammalian mRNAs (Wickens et al. 2000). Finally, another regulatory element of gene expression includes the post-translational control. This category composes of all the mechanisms that act after translation by modifying the protein levels. Such a mechanism is ubiquitination, which will have as a result the degradation of the ubiquitinated protein in the proteasome (Wang et al. 2013). In conclusion the transcription and translation are highly regulated processes and this take place due to the complexity of Eukaryotic cells, since strict regulation usually corresponds to high complexity. 2) Discuss the role of microtubules and their motor proteins in the motion of cilia and flagella. Microtubules are important elements for various cell movements, such as the chromosomal separation during mitosis and the motion of flagella and cilia. This movement, which happens along microtubules, is highly dependent on proteins that use energy from ATP hydrolysis in order to produce force and movement. These proteins are members of the kinesin and dynein families (Alberts et al. 2002). Cilia and flagella are plasma membrane projections dependent on microtubule formation, and are important for the movement in various eukaryotic organisms. In bacteria, the flagella structures are different from the eukaryotic flagella (Alberts et al. 2002). The movement of these structures has been extensively studied by using animal models, especially sea urchin models which appears to be a very powerful system for flagellar motility. Furthermore, the first scientists to observe this sliding mechanisms driven by dynein across the microtubules, were Summers and Gibbons by using dark-field microscopy (Hirose Amos 2012). In eukaryotic organisms the flagella and cilia are highly similar structures. Firstly, flagella are mostly found in sperm and many hair-like cellular projections with a core composed of microtubules (Cooper 2000). With their rolling motion they permit the cells to swim through liquid media. The cilia, are usually shorter than flagella but their organization tends to be similar. Their beating motion is like the breast stroke of the swimmers, and the cycles of adjacent cilia are quite asynchronous, thus producing the characteristic effect that can be observed through microscope (Alberts et al. 2002). The movement of both each flagellum and cilium is produced by the bending of each ones core, which is specifically termed as axoneme. The axoneme is a structure that is composed of microtubules in conjunction with their associated proteins in a regular and specific pattern. This pattern is composed by nine doublet microtubules which are fused together to surround a pair of microtubules. Th is formation is also known as the 9+2 pattern and is represented in the following picture (Cooper 2000). This type of arrangement is commonly seen in the majority of eukaryotic flagella and cilia forms. The length of these microtubules extends along with the length of the axoneme which can reach the 200 ÃŽÂ ¼m. At specific positions along the distance of microtubules, are located accessory proteins, providing with this a way a cross-bridging between the doublet microtubules. These molecules are dynein proteins, and are located around the perimeter of the axoneme (Cooper 2000). Dynein is a very large molecule (2000 kd), consisting of three heavy chains in conjunction with a variable number of intermediate and light polypeptides that have a weight ranging from 14 to 120 kd (Cooper 2000). The heavy chains are forming a globular domain which binds ATP and is responsible for moving along microtubules. The intermediate chains are responsible for the assembly of the dyneins. The light chains form two distinct groups, in accordance with the molecules that are related with. For example the first group is associated with the heavy chains, while the second group with the intermediate chains. In the cilia and flagella, there is also another specific dynein group, the intraflagellar transport (IFT) dynein, which is important for the association and disassociation of these organelles, and also have transport properties of either membrane proteins or even the IFT themselves (Hirose Amos 2012). The ciliary dyneins, are composed of a different set of arms, the outer dynein arms and a more complex set of inner dynein arms. Each one of this structures plays a different role in the ciliary movement. The outer dynein arms are responsible for the production of the majority of the force required for the ciliary movement, while the inner dyneins, are mostly providing a precise control of this movement (Hirose Amos 2012). Another important feature of the cilia and flagella, is that the minus ends of each microtubule are anchored in a structure which is named basal body. This is highly similar to the centriole, and is necessary for the arrangement of the axoneme microtubules. Each one of the doublets located in the outer part of the flagella or cilia, is formed by the extension of two of the microtubules of the basals body triplets (Cooper 2000). The movement of cilia and flagella is caused by the relative sliding of outer microtubules, driven by the activity of axonemal dynein, and the mechanism is represented in figure 3. The dynein bases attach with the A microtubules while the head of each dynein attaches with the B microtubule. With the green color is represented the nexin link, which binds the microtubules in the axoneme. When the one doublet of microtubules, bends along with the other one, the resulting movement is bending, which is the source of the beating movements of cilia and flagella (Alberts et al. 2002). Scientific evidence suggests that upon ATP hydrolysis the dyneins change their conformational state (Hirose Amos 2012). 3) Describe the most important classes of molecules that participate in common signal transduction pathways In signal transduction pathways, extracellular signals such as hormones or other molecules are registered by membrane receptors and the signal is being transferred inside the cell by a set of reactions. This signal transduction can be mediated by two distinct mechanisms. The first one includes the use of receptors, and other proteins including enzymes. The second one contains a set of molecules which are known as second messengers, that regulate the intracellular signaling (Boon 2009) . The intracellular second messengers, are signal molecules that reach their target by diffusion. They can be divided into two different groups, those with a hydrophobic character (diacyl glycerol or phosphatidyl inositol) and the hydrophilic ones. The hydrophobic messenger are located on the membrane and they can reach the proteins located on the membrane by diffusing through the plasma membrane of the cell. The hydrophilic messengers are located in the cytoplasm and their targets are located in the cytosol as well (Boon 2009). The most important second messengers include the cAMP, cGMP, inositol phosphates, calcium ions, diacylgrlycerol and phosphatidyl inositol phosphates. 3-5 cyclic AMP (cAMP) Is among the most important second messengers and regulates a variety of cellular functions, such as glycolysis, muscle contraction and ion transport. The intracellular concentration of cAMP is regulated by two factors, the adenylyl cyclase and the phopshodiestarases. The former is important for the cAMP synthesis while the latter for its degradation. The activation of adenylyl cyclase is dependent to G-protein coupled receptors and involves the participation of GÃŽÂ ± and GÃŽÂ ²ÃƒÅ½Ã‚ ³ proteins. The degradation of cAMP mediated by cAMP phosphodiesterases, which are being regulated by Ca2+/calmodulin and also by phosphorylation (Boon 2009). In the majority of the cases, the target of the high cAMP concentration is the activation of protein kinases A (PKAs). Initially, in the absence of cAMP the PKA is organized as a tetramer, with two catalytic and two catalytic subunits, and the protein kinase is inactive. When cAMP concentration is increased by adenylyl cyclase, leads to the binding of two molecules to the regulatory subunit and the tetramer dissociation and activation of PKA (Boon 2009). cGMP In the same manner with cAMP, the 3-5-cGMP is extensively spread in the intracellular space. Like in the case of cAMP , the cGMP is formed by guanylyl cyclase from GTP. The cGMP can activate cGMP-dependent protein kinases, after binding to specific locations. In contrast to the PKA kinases, the activation of cGMP-dependent protein kinases is dependent to only one protein chain of these proteins. Specifically, the binding of the cGMP to the regulatory domain of the protein, activates it and permits phosphorylation of other substrates (Boon 2009). Inositol Phosphates The inositol containing phospholipids located in the plasma membrane, are the starting points for the production of many inositol messengers as a response to extracellular or even intracellular signals. The inositol phosphates are important players for the regulation of phospholipase C, which is a very important enzyme in the metabolism of phosphatide inositol. Another important function of these phosphates, is the recruitment of Ca2+ ions that are inside storage organelles, such as mitochondria. The calcium ions are among the most ubiquitous targets of second messengers, and regulate a vast array of actions (Boon 2009). Calcium ions The calcium ions can have a regulatory character in many ways, according to the time, frequency and amount of release rate. This feature, explains the complexity of Ca2+ signals. Still it is not understood how oscillatory calcium signals are regulating various processes. It has been suggested that CaM kinase II participates in the formation of repetitive calcium signals. The high intracellular concentration of calcium is temporary and usually a local phenomenon. The cell contains a variety of transport systems, which can transfer the calcium ions inside the storage locations. These transfer mechanisms are Ca2+ ATPases, which transfer calcium against the concentration gradient. Another mechanism, is the sodium-calcium exchange proteins which are mostly apparent in muscle cells (Boon 2009). Diacylglycerol and phospatidyl inositol phosphates The diacylglycerol is being produced by the metabolism of the membrane phosphatidyl inositol phosphate, after the effect of two distinct enzymes, the PLCÃŽÂ ³ and PLCÃŽÂ ². The diacylglycerol (DAG) is then responsible for activating the protein kinase C, which plays an important role in cell proliferation through phosphorylation of various substrate proteins (Boon 2009). Except of DAG, the metabolism of phosphatidyl inositol diphosphate, produces the inositol triphosphate, which increases intracellular calcium levels by binding to specific receptors (Boon 2009). Conclusively, signal transduction is a highly regulated mechanism, which permits the transmission of an extracellular signal inside the cell, and a subsequent cellular response. Among the most important molecules that are participating in this process, we distinguished some members of the family of the second messengers, such as calcium ions, diacyl glycerol and phosphatidyl inositol. 4) Describe the steps of neurotransmission. The process of neurotransmission can be divided into five distinct steps. The first includes the synthesis of the neurotransmitter, the second the storage of the neurotransmitter into transport vesicles, the third the influx of calcium and exocytosis of neurotransmitter, the fourth the binding of the neurotransmitter at the postsynaptic membrane and the fifth the deactivation of the neurotransmitter. The low weight neurotransmitters are synthesized in the cytoplasm of the cell, where enzymes act and convert them into mature neurotransmitters. These enzymes are produced in the neuronal cell body and are transferred to the presynaptic terminal via the slow axonal transfer system. When the new transmitters are synthesized in the cytoplasm, certain mechanisms need to follow for transporting them to the synaptic membrane. On the other hand, the neuropeptides which is the other category of known neurotransmitters, are produced in the neuronal cell body, and need to be transferred a long distance in order to reach the site of secretion. For this reason, they are transported from the soma of the neuron to the presynaptic terminal with the fast axonal transport (Hyman et al. 2009). The small-molecule neurotransmitters, such as acetylcholine and amino acids, are stored into vesicles of 40-60 nm diameter. The primary characteristic of these vesicles, is that in electron micrographs they appear with a clear center area. The storage, requires specific proteins which are located in the membrane of the synaptic vesicles in the presynaptic neuron, the vesicle monoamine membrane transporters (VMAT). In contrast to the small-molecule neurotransmitters, the neuropeptides, are stored into synaptic vesicles with a larger size (90 to 250 nm). In electron micrographs, they seem to have a center relatively more dense than the synaptic vesicles of the small neurotransmitters (Purves et al. 2001). After the influx of calcium into the pre-synaptic cytoplasm, it begins the process of neurotransmitter release. The first step of this exocytosis, includes the docking of the synaptic vesicle membrane at the active zones plasma membrane. The second step is priming. This corresponds to an ATP dependent maturation of the synaptic vesicles that are being docked in the membrane of the active zone but cant be induced by Ca2+. The result of this maturation, is that the primed vesicles can immediately release their content after a Ca2+ influx. The third step of this process includes the fusion of the synaptic vesicle with the presynaptic membrane, which allows the exocytosis to happen. In this step, the function of the protein synaptotagmin is of high importance, since it senses the levels of Ca2+ and regulates with this way the fusion of the vesicles. The final step of this step includes the quantal release of the neurotransmitter with a mechanism of exocytosis. The exocytosis is synchroni zed with the influx of Ca2+ and its induction is controlled by the depolarization of the nerve terminal. After the release of neurotransmitter at the synaptic cleft, the membrane of the vesicle will be recycled with a process of endocytosis (Hyman et al. 2009). After the exocytosis, the neurotransmitter starts to diffuse across the synaptic cleft and targets the post-synaptic neuron and its receptors which are localized on the membrane. The binding of the neurotransmitter to the postsynaptic membrane, will cause both biochemical and electrical alterations. Specifically, an excitatory signal will depolarize the membrane and thus a positive charge will pass inside the cell. This depolarization is caused by the opening of sodium channels located on the post-synaptic membrane, which permits the influx of sodium ions across the membrane. On the other hand, an inhibitory signal will hyperpolarize the cell, and thus a positive charge will flow with a direction outside of the cell. This hyperpolarization is induced by an inhibitory postsynaptic potential (IPSP) which cause the influx of chloride ions, which make the membrane potential more negative and the propagation of the action potential significantly more difficult (Hyman et al. 2009). When a neurotransmitter finishes its function, the next step is to be removed from the synaptic cleft. When the local neurotransmitter concentration falls, the neurotransmitter unbounds from the post-synaptic receptor. After this, the neurotransmitter can be either degraded by specific enzymes, or reuptaken by high affinity receptors. The latter corresponds to the most common way of neurotransmitter removal, and includes the reincorporation of the neurotransmitter into the pre-synaptic terminal by endocytosis. This permits the neurotransmitter to be recycled inside the cell. The remaining percentage of neurotransmitters, follows the other path of removal which corresponds to the enzymatic degradation. A characteristic enzyme is acetylcholinesterase (AChE) which degrades the neutrotransmitter acetylcholine into acetate and choline. Another examples of such enzymes include catechol-o-methyltransferase (COMT) and monoamine oxidase (MAO) (Naik 2015). 5) Describe with examples the major mechanisms of action of the different types of neurotransmitter and hormone receptors. In 1907, the physiologist Langley, introduced the aspect of receptor molecules, in order to explain specific properties of molecules on muscle and nerve cells. The neurotransmitter receptors are proteins located in the post-synaptic plasma membrane and contain an extracellular site, specific for the binding of a neurotransmitter. The neurotransmitters, have two distinct families of receptors. The first one, the ligand-gated ion channels or ionotropic receptors, combine the properties of ion channels by having also a neurotransmitter binding domain on their outer part of the membrane. The other family of receptors, are the metabotropic receptors, because the movement of ions depends on certain metabolic steps. The important difference of these channels with the ionotropic channels, is that they dont have an ion channel in their structure, in contrast they have a domain which affects the channels through activation of G proteins, and these receptors G protein coupled receptors (Purves et al. 2001). G protein coupled receptors (GPCRs) are the largest family of membrane protein signaling molecules. The activation of these proteins can be achieved by various ligands, thus modulating the activity of a diverse set of signaling pathways (Kobilka 2007). Nowadays, it is estimated that the human organism contains approximately 800 unique GPCRs, and the 460 of them are assumed to be olfactory receptors (Fredriksson et al. 2003). Their main characteristic is that they contain seven transmembrane-spanning segments, which coordinate the position of the proteins N-terminus at the extracellular space and C-terminus at the intracellular space. Studies in neuromuscular synapse, have demonstrated in detail the neurotransmission mechanism. The binding of the acetylcholine to the postsynaptic receptors, leads to the opening of ion channels. Specifically, the binding of two Ach to a receptor, causes an influx of sodium for milliseconds. In real situations, when an action potential reaches a presynaptic neuron, millions of ACh molecules are secreted into the synaptic cleft. As a result, a high number of AChs will bind to numerous receptors, located on the postsynaptic membrane. The opening of these channels will cause the membrane to depolarize, and the opening of voltage-gated sodium and potassium channels (Purves et al. 2001). When the postsynaptic membrane potential becomes more negative even from the resting potential, the end plate current increases, and decreases when the membrane potential is more positive. At very positive potential, there is a reverse polarity which cause the current to convert form an inward to an outward one (Purves et al. 2001). The other category that we will discuss, the hormones, are produced most of the times by specific cells, and initiate a reaction in certain cell types. Only the cells that have hormone receptors, can be used as hormone target cells. These receptors, recognize certain hormones according to their chemical structure. The classes of these receptors are two, the membrane bound receptors, which are transmembrane proteins and the second category the intracellularly localized receptors which are intracellular receptors (Boon 2009). The membrane bound receptors have an extracellular domain which is linked with an intracellular one. The binding of a hormone are following the rules of noncovalent interactions. In general, signaling molecules for example adrenaline, binds to their receptors with a very high affinity, even higher than the one observed between an enzyme and a substrate. After the binding and the recognition of adrenaline by the receptor, this signal is converted into an intracellular signal, which targets the nuclear compartment. According to the type of the receptors which will bind, adrenaline can cause inhibition of insulin secretion, glycogenolysis and glycolysis (Boon 2009). Furthermore, the hormone insulin, uses for signal transduction a set of tyrosine kinases receptors. The receptors that have tyrosine kinase (TK) activity (RTKs), contain a specific domain for binding ligand molecules located on the extracellular side. Inside the lipid bilayer there is a single alpha-helical element, and inside the cytosol another part that harbors a TK domain. When the RTKs are not bound with the ligand molecule, most of them are in their monomeric state. The only exception of this paradigm is the insulin receptor and in general its family members. When extracellular stimulus is absent, in our case insulin, the kinase domain of the receptors remains in its inactive, auto inhibited state. In this phase, the receptors either have very low kinase activity, or they havent at all. After the binding of insulin on the receptor, the consequent transformational changes that lead to the activation of the TK domain. The activation process of TK includes a trans-autosphorylation of tyrosine residues at segments inside and outside of the TK domain. Then, the phosphorylated P-Tyr which is formed at the site of receptor, becomes a docking region for proteins that harbor phosphorylated tyrosine specific domains. Such proteins are SH2, phosphotyrosine-binding (PTB) and C2 .This signaling eventually leads to an increase of the number of glucose transporter 4 in the outer membrane of specific cells, and thus the increased reuptake of glucose from the blood (Boon 2009). Bibliography Alberts, B. et al., 2002. Molecular Biology of the Cell,   Ã‚   Black, D.L., 2000. Protein Diversity from Alternative Splicing: A Challenge for Bioinformatics and Post-Genome Biology. Cell, 103(3), pp.367-370. Available at: http://www.sciencedirect.com/science/article/pii/S0092867400001288. Boon, E.M., 2009. Biochemistry of Signal Transduction and Regulation, Available at: http://www.journals.uchicago.edu/doi/10.1086/603489. Cooper, G., 2000. The Cell: A Molecular Approach 2nd editio., Sunderland (MA): Sinauer Associates. Available at: https://www.ncbi.nlm.nih.gov/books/NBK9833/. Fredriksson, R. et al., 2003. The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints. Molecular pharmacology, 63(6), pp.1256-72. Hirose, K. Amos, L.A., 2012. Handbook of Dynein. In Handbook of Dynein. pp. 12-16. Hyman, S. et al., 2009. Molecular Neuropharmacology: A Foundation for Clinical Neuroscience, Second Edition. In Molecular Neuropharmacology: A Foundation for Clinical Neuroscience (2nd ed.). pp. 265-266. Available at: https://www.amazon.com/Molecular-Neuropharmacology-Foundation-Clinical-Neuroscience/dp/0071481273. Kobilka, B.K., 2007. G protein coupled receptor structure and activation. Biochimica et biophysica acta, 1768(4), pp.794-807. Available at: http://www.ncbi.nlm.nih.gov/pubmed/17188232%5Cnhttp://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC1876727. Latchman, D., 2007. Gene Regulation, Available at: http://books.google.com/books?id=4x3ZzLNyfDsCpgis=1. Naik, P., 2015. Biochemistry, JP Medical Ltd. Purves, D. et al., 2001. Neuroscience. 2nd edition. Sinauer Associates. Available at: https://www.ncbi.nlm.nih.gov/books/NBK11166/. Wang, X., Pattison, J.S. Su, H., 2013. Posttranslational modification and quality control. Circulation Research, 112(2), pp.367-381. Wickens, M. et al., 2000. Translational control of gene expression. , 37(6), p.295.

Narrative of the Life of Frederick Douglass Essay -- Papers

Narrative of the Life of Frederick Douglass Narrative of the Life of Frederick Douglass, depicts a vivid reality of the hardships endured by the African American culture in the period of slavery. One of the many things shown in Frederick's narrative is how slaves, in their own personal way, resisted their masters authority. Another is how slaves were able to create their own autonomous culture within the brutal system in which they were bound. There are many examples in the narrative where Frederick tries to show the resistance of the slaves. The resistors did not go unpunished though, they were punished to the severity of death. Fredrick tells of these instances with a startling sense of casualness, which seems rather odd when comprehending the content of them. He does this though, not out of desensitization, but to show that these were very commonplace things that happened all over the South at the time. One example that Frederick mentioned in the subject of resistance of the slaves against the masters is when he was under the charge of Mr. Gore. A slave by the name of Demby was getting whipped for a mistake he made. After Demby received but a few stripes he ran and jumped into a creek to the depth of his shoulders and refused to come out. This took great bravery considering Mr. Gore had a famous reputation for being nasty to slaves. Demby was given to the count of three to get out of the creek or he was to be shot, knowing the consequences Demby still refused to get out. He was then shot in the face by Mr. Gore with a musket. Demby truly resisted his master at the greatest cost he could have paid, his life. Another example given by Frederick in his narrative of how slaves were able to ... ...laves to be drunk during this time; in fact, they often got angry if they weren't drunk. Frederick feels that the master tries to make the slaves sick of freedom during this holiday time, by showing them only the abuse of it rather than the good. There was also a mention of a couple of "classes" among the black slaves. Slaves, from the viewpoint of Frederick, I feel, had a sort of "slave-class". The richer your master was the higher class you were, the poorer your master was the lower class you were. "To be a poor man's slave was a disgrace indeed!", was what Frederick mentioned of the issue. As you can see Frederick Douglass provided many glimpses into the world of slavery in his narrative. He showed many different examples of how slaves were able to resist their masters and create their own autonomous culture within the brutal system of slavery.

Describe and Compare the Two Forms of Cubism

According to the Tate Gallery’s exposition (1979) Cubism has remained the most important and influential movement of the 20th century, notwithstanding the movement’s short duration. According to Read (1994) the major period for Cubism was from 1907 to 1914, with Picasso and Braque as the main originators of the movement. The rationale for the Tate’s statement is given as â€Å"the artists associated with [Cubism] took some of the most decisive steps towards abstraction†, and this extreme development â€Å"has become the archetype of later revolutionary movements† (p. 84). The movement, according to Read, was the first abstract style of the 20th century, and named by the art critic Louis Vauxcelles, who took up a remark by Matisse about â€Å"Braque’s little cubes† (p. 100). One source (artlex. com) cites Vauxcelles as saying: â€Å"M. Braque scorns form and reduces everything, sites, figures and houses, to geometric schemas and cubes. † One of the most innovative developments is that the creators of Cubism sought to replace a single viewpoint and light source, normal within the western art world since the Renaissance, with a much more complete representation of any object, combining many ‘aspects’. Initially colours were temporarily abandoned and shapes were simplified and flattened. Space was furthermore rendered by means of oblique lines and overlapping forms (The Tate Gallery, 1979). According to Belton (2002, p. 109) Picasso and Braque both struggled with the problem of representing three dimensional objects and figures in the two dimensional medium of painting; â€Å"their solution was to create an abstract form that could display two or more sides of an object simultaneously†. Whilst Picasso’s Demoiselles d’Avignon is generally viewed as the first Cubist painting, Read (1994) argues that the painting might be more usefully viewed as ‘pre-Cubist’, or ‘proto-Cubist’, as it was so heavily influenced by Iberian or African art. Cezanne’s later work is often viewed as the catalyst for the development of Cubism, and Read cites Cezanne’s advice to Bernard â€Å"to deal with nature by means of the cylinder, the sphere and the cone† (p. 100). Cezanne, by trusting his eyes and attempting to express natural, binocular vision, allowed for the ‘truth’ of the shifted viewpoint (Moszynska, 1990). Cubism gives the artist a way of depicting the world in a way that goes beyond what can be seen, and attempts to deal with the energies of objects. According to Read (1994) Cubism could be categorized into various divisions, including ‘analytic’, ‘hermetic’ and ‘synthetic’. This essay will mainly concentrate in the analytic and synthetic forms of Cubism. The term ‘hermetic’ refers to the largely or wholly indecipherable way of representing an object in the flatter type of abstraction, as typical of both Braque’s and Picasso’s later way of working. In this phase the allover pattern became more important. Other sources (including artlex. com) refer to ‘analytic’ cubism as ‘facet’ cubism. Analytical and Synthetic Cubism acquired their names through the comments by art historian Einstein, and in effect are retrospective labels. Einstein wrote that the â€Å"simplistic distortions† employed by Picasso, as typified by his portrait of Gertrude Stein, led to â€Å"a period of analysis and fragmentation and finally to a period of synthesis† (as cited in Foster, Krauss, Bois and Buchloh, 2004, p. 106). The analytical phase of Cubism, as developed by Braque and Picasso, was characterised by a number of different features, starting with the contraction of the painters’ palettes, away from the full colour spectrum to rather monochrome selections, which Foster et al. term ‘abstemious’. The second characteristic is the extreme flattening of the visual space, â€Å"as though a roller had pressed all the volume out of the bodies† (ibid. , p. 106). The third characteristic identified by Foster et al. is the visual vocabulary used to describe â€Å"the physical remains of this explosive process† (p. 06). Foster et al. illustrate these features with Picasso’s portrait of Daniel-Henry Kahnweiler (1910) and Bracque’s painting The Portuguese (The Emigrant, 1911-12). The grey or tonal scale, the traditional tool of representing volume, is used very differently by the Cubists. Kahnweiler, the art dealer who exhibited both Braque and Picasso’s work, identified the â€Å"bringing about the unity of the pictorial object† as the exclusive concern of Cubism (Foster et al. , 2004, p. 107). Kahnweiler’s view as upheld by Greenberg, who saw Analytical Cubism as the fusion between two types of flatness: the â€Å"depicted flatness†, shoving the fragmented objects closer to the surface, and the â€Å"literal flatness† of that surface (ibid. , p. 109). Foster and his colleagues however question this: they note a number of differences between the evident intentions of Braque and Picasso in relation to the flat plane, with Picasso, being more ‘tactile’, more focused on exploring the possibilities of using Cubism for sculpture, and Braque more concerned with transparency. Steinberg too, urged against the blurring of Picasso and Braque’s pictures. The two exponents of Cubism saw themselves as being ‘roped together’ like mountaineers in their exploration of this new way of working, with the ebullient Spaniard referring to Braque as his ‘wife’. However, Braque was loyal to ‘passage’, the practice of visual slippage between adjacent elements, whereas Picasso, according to Foster et al. , had an â€Å"overwhelming concern with a vestigial kind of depth† (ibid, p. 109). Picasso seemed more focused on making depth tactile, as Foster et al. demonstrate with showing Picasso’s central plunging depth in Houses on the hill: Horta de Ebro (1909). They go on to argue that Braque is more concerned with the ‘diaphanous’ quality of Cubism, with the loss of traditional notions of figure and ground The Tate Gallery (1979, p. 85) presents Braque’s Clarinet and a Bottle of Rum on a Mantelpiece (1911) as a crucial point in Cubism, â€Å"when the breaking down of objects had been carried to a point very close to complete abstraction†. After this point Braque and Picasso started to introduce areas of wood-graining, the use of collage, and a re-introduction of colour, thereby representing objects in a more recognisable, but also more symbolic way. According to Gersh-Nesic (n. d. ) Synthetic Cubism integrates â€Å"high† and â€Å"low† art (art made by an artist combined with art made for commercial purposes, such as packaging), and according to some can be considered the first Pop Art. Even before 1912 Braque and Picasso had introduced stenciled lettering into their paintings. These stencils were not fine art, they were used for packaging and pub signs. The stencils draw attention to the surface of the canvas, since the uniform letters appear independent of what's painted underneath them. Two technical innovations exemplify new development in Cubism: papier colle and collage. Papier colle involves sticking coloured paper onto the canvas and was invented by Braque. Collage was developed by Picasso, and involved sticking all sorts of materials, such as leather, newspaper, material and rope, onto the surface. Sticking different materials, such as woodgrain, onto the surface of the painting playfully confused what was real and what was an illusion (Tate, n. d. ). New, provocative questions are raised with the use of collage, namely: what is more realistic, to perfectly simulate the look of a newspaper in oil paint, or to stick actual newspaper onto the canvas? (Tate, n. d. ). Wadley (1970, p. 13) holds that â€Å"technically and conceptually† Synthetic Cubism was â€Å"a denial of the European tradition†, in that the surface was now the furthest point from the spectator, not the nearest. Artists working in a synthetic way started with the terms of painting, and from them composed an image which they could justly claim was more real, â€Å"since it in no sense distorted or imitated something else† (ibid. p. 14). Gris, who was the clearest formulator of cubist theory, stated: I work with the elements of the intellect, with the imagination. I try to make concrete that which is abstract. I proceed from the general to the particular, by which I mean that I start with an abstraction in order to arrive at a true fact. Mine is an art of synthesis, of deduction. (ibid. , p. 129) Gris was called a ‘demon of logic’ by Apollinaire. Indeed, his way of working and thinking was different from his Cubist colleagues. According to Wadley the integration in Gris’ work is tighter than in comparable Picassos or Braques. Gris used collage only in his paintings, and its effect is always to strengthen the rigid division of the surface. [ ]There is no hint of Picasso’s ragged edges and random encounters, nor of Braque’s simple elements floating in a spacious arena. The total effect is of tight concentration. (Wadley, 1970, p. 82) Gris’ meticulous style is evident in how he has painstakingly arranged the letters in ‘Le Matin’ in Man in the Cafe, to correspond with the diagonal columns and echo the horizontal line elow (ibid). Foster et al. (2004) make a ‘semiotic’ reading of Picasso’s use of material in his Violin (1912): the ‘twin’ pieces of newsprint paper represent on the one hand the frontal, opaque (wood of the violin), as well as the transparent, amorphous ‘ground’ (background colour). They go on to claim that a similar visual play of meaning is evident in Picasso’s Bottle of Vieux Marc, Glass and Newspaper (1913), where a piece of wallpaper is used to represent the liquid in the glass, the rim of the glass, and the ground of the table-cloth. The cut out piece used for the liquid (looking like a chef’s top hat) represents transparency, whilst the ‘negative shape’ left by the incision represents the solid stem of the glass. The viewer might be left with the question whether the ever playful Picasso was just enjoying a visual pun, or whether he intended any of this to be read as ‘signs’. The artist himself stated: â€Å"Mathematics, trigonometry, chemistry, psycho-analysis, music and whatnot, have been related to cubism to give it an easier interpretation. All this has been pure literature, not to say nonsense, which brought bad results, blinding people with theories. (Wadley, 1970, p. 128) During its lifetime both Analytical and Synthetic Cubism encompassed and influenced many artists – the most notable of these being Leger, the three Duchamp/Villon brothers, Robert and Sonia Delaunay, Gleizes and Metzinger (who published a book on Cubism). For some of these artists Cubism functioned as a transition, although Picasso would hold that â€Å"Cubism is neither a seed, nor a foetus, but an art dealing primarily with forms, and when a form is realized it is there to live its own life† (Wadley, p. 28). It led artists like Piet Mondrian to what he saw as its logical end, complete abstraction. Cubism may have been short-lived as a movement, but it continues to influence contemporary art to this day. Collage, for instance, has become a widely practiced form of art. And in terms of form, the practice of reducing everything to the ‘cylinder, the sphere and the cone’ was brought to mind on viewing some of Manolo Valdes’ work, in an exhibition in The Hague this summer.

Central Heating

THE HISTORY OF CENTRAL HEATING Brittany Science, 4th, Mr. Leetch, History of an Invention 2/8/13 The History of Central Heating Systems By Brittany Hicken I. Who invented the central heating system? A. We don’t know exactly who invented the first one B. Ancient Romans created the hypocaust C. Greeks created their own version of the hypocaust D. Sergius Orata (80 B. C. ) E. Louis Savot- French (1600) F. Dalsme (1600) G. Dr. John Clarke (1652) H. Benjamin Thompson (1796) I. Count Rumford (1796) J. William Cook (1745) K. William Strutt (1805) L. Eliphalet Knott (1833) M. Isaac Orr (1836) N. Professor Warren Johnson (1873)O. Milton Fessler (1905-1908) II. What were the changes over time? A. It was first the hypocaust, we don’t know when it was invented B. Fixed central hearths date back to 2500 B. C. , they were excavated in Greece C. An under floor heating system was installed in the house of King Arzawa in Beycesutan, Turkey in 1300 B. C. D. The Romans brought technology to a high standard, by creating systems designed by Sergius Orata E. Crude fireplaces were made around 800 A. D. these were widespread in Europe in the 1300’s F. After the 14th century, the next important event was the chimney.Early chimneys were large, so to allow chimney sweepers to climb into them G. Masonry stoves became very common in the 1500’s H. Louis Savot invented the raised grate system and designed a circulating fireplace in the early 1600’s I. The way of stove heating soon had advanced. The first free standing stove, or not connected to anything so it’s not mounted to anything, was the Furnus Acapnos or the smokeless stove invented by Dalsme in France in the later days of 1600’s J. The earliest stove to be introduced to North America is the iron box stove invented by Dr. John Clarke in about 1652 K.William Cook was the first to propose the way of steam heating in 1745 L. M. Bonne constructed an actual hot water heating system instead o f the steam heating system in the late 1700’s M. William Strutt invented a warm air furnace that included of a riveted, wrought iron air chamber encased with bricks. The rivets help seal the air chamber to be air tight, in 1805. This chamber has ducts fed with heated air into rooms. Strutt’s hot air furnaces were referred to as cockle, belper, or derby stoves N. In 1833, Eliphalet Knott invented the stove with base burners O.In 1836, Isaac Orr invented the airtight stove so there would be no heat loss on the inside chamber P. Professor Warren Johnson taught at a school up in Wisconsin and back then the only way to change the temperature was to run downstairs and tell the janitor to turn the wheel in a way to let either more steam or less steam into the room. He later created and patented a thermostat that relied on compressed air to make the valves work. He then later created the Johnson Electric Service company Q. â€Å"Coal-less† Mondays were introduced in 191 7 saving coal and stimulating the use for oil and gas since there wasn’t much coal around.R. Milton Fessler invented residential oil burner in California so that residents could have their house easily heated without stoking coal ever hour between 1905-1908 S. By 1926, the Electric Refrigeration News began to publish, â€Å"heating had advanced from the campfire to something so silent, so automatic that we just take for granted and ‘just turn the heat on’ III. When did initially stop changing and industries stated introducing something different and not a huge improvement? A. From the mid 1920’s-1936 B. People started to take the silent heating system for granted C.People were inventing little accessories or little parts to go on to the latest thing but nothing much bigger or more important happened IV. Where did the inventions take place? A. Rome B. Greece C. France D. The United States E. Turkey F. Europe V. Why it was initially created? A. To heat bath water in the Roman Empire B. To heat homes so that people could live comfortably C. To heat specific rooms D. The thermostat was created to control the amount of wanted heat in any specific room, or house VI. What was the hypocaust and how did the hypocaust work? A. The word â€Å"hypocaust† refers to a subfloor radiant heating system B.The word hypocaust come from the Latin word â€Å"Hypocaustum† which meant burning underneath C. These were important to ancient romans because it heated their baths and as well as large rooms D. The small pillars of stacked bricks would have supported a fire proof floor that was heated by air circulation under the floor in a chamber with an external furnace E. The hot gases at the top of this hypocaust below the floor would have been up to about 400 degrees Fahrenheit F. Addition to the hypocaust, some romans had hollow walls to help keep even temperature and prevent condensationWorks Cited By Brittany Hicken A Brief History of Heatin g and Cooling America 0Homes. †Ã‚  Sustainable Dwelling. † William Furr, 10 Jan. 2011. Web. 27 Jan. 2013. â€Å"Archrnews. com. †Ã‚  Archrnews. com. N. p. , 12 Nov. 2001. Web. 4 Jan. 2013. http://www. achrnews. com/articles/an-early-history-of-comfort-heating â€Å"A Short History of Central Heating. †Ã‚  Taco. N. p. , 2012. Web. 20 Jan. 2013. â€Å"Hypocaust. †Ã‚  About. com. N. s. Gill, n. . Web. 11 Jan. 3013. Duffy, Catherine. â€Å"Who Invented the Central Heating System? †Ã‚  EHow. Demand Media, 04 Nov. 2009. Web. 20 Jan. 2013. This paragraph is a run though of the timeline events. Going all the way back to 3000 B. C. the first Hypocaust was born. Ancient Romans had invented the hypocaust. The hypocaust is an under floor heating system that is a chamber that collects heat and leaves it under there. Going up to 2500 B. C. the first fixed central hearths were first excavated in Greece. In 1300 B. C. King Arzawa had an under floor heatin g system installed into his palace in Turkey. Later in 80 B. C. Sergius Orata started to create designs for heating systems and brought technology to the Romans. Crude fireplaces were made around 800 A. D. and were later widely spread throughout Europe in the 1300’s. The chimney was invented around the 1400’s. They were large in diameter so that the Chimney Sweepers could fit up into them to clean them out. 100 years later in 1500, masonry stoves became the â€Å"new thing† to have.They also became very common. Louis Savot invented the raise gate system and designed a circulating fireplace. In early 1600’s, the first standing stove, or not connected to a wall or mounted to anything, was the Furnus Acapnos, or the smokeless stove, invented by Dalsme. He also introduced fresh fuel in the same opening as combustion air, directing all combustion products over already-burning fuel, a design that ensured complete combustion. The iron box stove, the earliest sto ve to be introduced into North America, was invented by Dr. John Clarke.William cook was the first to propose the way of using steam to heat up rooms, in 1745. In the late 1700’s, M Bonne invented an actual hot water heating system instead of William Cook’s steam heating system. In 1805, William Strutt invented a warm air furnace that had a riveted, wrought iron air chamber encased with bricks. This chamber had ducts that fed into rooms and blew heated air into the rooms. The way this chamber was built was to keep the hot air from escaping from the chamber and having heat loss. They were referred to as cockle, belper, or derby stoves.Isaac Orr invented the airtight stove so there would be no heat loss inside the chamber in 1836. Professor Warren Johnson taught at a school in Wisconsin, where the only means of room temperature control was to tell the janitor to go to the basement and adjust steam valves. Johnson developed an electric annunciator system in 1873 that was used to signal the janitor when heat needed adjusting. He continued experimenting and in 1885, patented a thermostat that relied on compressed air to operate steam valves. He then established the Johnson Electric Service Co. to manufacture and install his system.Johnson went on to invent the humidistat for control of the humidity in buildings in 1905. In 1905-1908, Milton Fessler invented a residential oil burner so that residents could have their own house heated easily without stoking coal in a fireplace every hour. Coal-less Mondays were introduced in 1917 to save coal and stimulate the use for oil and gas since there wasn’t much coal around or to be found regularly. In 1926, the Electric Refrigeration News began to publish that heating had advanced from the campfire in a cave, to something so silent, so unnoticeable.And in present day, thermostat controls air and ducts are fed in a way we can’t see the m and as well as fed to each room through a vent in which air i s blown out of. We take advantage of just â€Å"turning on the heat† every day that we don’t even bother to thing what had to happen way back when to heat thing up. The way of heating has been a system that not everyone thinks about. It has gone from the campfire, to the hypocaust, to stoves, to compressed valves, to thermostats, to an automatic heating with the push of a button. Over time, the way of heating has improved and impressed many along the way.It used to be having a chimney and stoking coals for five minutes ever hour just to keep the coals burning and hot and giving off heat. To progress this way of heating, there cannot be only one inventor. There are many who have created accessories, or major parts to different systems. The inventors go from ancient Roman empires and ancient Greek empires to people we have never heard of, but have improved life as we know it tremendously. This is the way of heating. Going into B. C. years, there were some unknown dates a nd some known dates. First was campfire.We all have heard off the story where cavemen are in a stark cold cave with a campfire. That’s just an obvious fact. Later on the hypocaust was made my ancient Romans and ancient Greeks. The word hypocaust refers to a subfloor radiant heating system: suspended floor with space for gases and hot smoke. The word hypocaust comes from the Latin  word Hypocaustum  which originally meant a ‘burning underneath'. Hypocausts were very important to Roman’s system of heating. The hypocaust heated baths and large rooms. Along with the hypocaust, there were sometimes hollow walls in ancient structures.These hollow walls would help maintain even temperatures as well as eliminate condensation. The small pillars of stacked bricks would have supported a fireproof floor that was heated by means of air circulation in the under floor chamber with an external furnace as heat source. The art and science of the hypocaust systems was lost afte r the fall of the Roman Empire. Western heating science had advanced very little in the period of the Dark Ages. Around 2500B. C fixed central hearths were excavated in Greece. In 80 B. C. Sergius Orata brought high art designs to Roman technology.At first Romans were only heating up their floors, but later used heated walls and some were designed as early as warm air heating systems. By this, introducing heated air through floor openings. This is the end of the B. C. heating ways. Now going into the A. D. times, from 1600-1800 specifically. In the late 1600’s, Dalsme invented the first freestanding stove, not mounted to a wall, called the Furnus Acapnos to the smokeless stove. He also introduced fresh fuel in the same combustion air directing all products over already burning fuel, a design that ensured itself. The smokeless stove was a great advance but, it was accepted slowly.The earliest stove introduced into North America was the cast iron box stove which was invented by Dr. John Clarke in 1652. This kind of stove was originally made in Holland and later imported into England after1600. Louis Savot invented a raised gate system and designed a circulating fireplace. He used a hollow iron bottom and back in a hearth, at which cold air entered the bottom, was warmed, and entered the room through openings, in early 1600’s. In 1653, Sir Hugh Platt proposed using hot water to dry gun powder and Sir Martin Triewald proposed warming greenhouses with hot water.This might be referred to as the hydronic system, which is the heating of an object by water. In 1735, John Desaguiliers designed the first modern heating blower which was turned by hand by an operator referred to as the ventilator for the British Houses of Parliament. The design of centrifugal, acting from or away from the center, blowers was continually improved in England and Europe during 18-19 century. The early fans were mostly operated by steam engines. In the late 1700’s, M. Bonn e in France constructed an actual hot water heating system using a boiler.The French idea was introduced into England by the Marquis de Chabannes later in 1816. By the 1790’s, the steam heating way had only progressed in England, being used to heat mills and factories. The advantage of steam heating is the avoidance of the expense of insurance. This is the end of the 16th and 17th century. Moving ahead to the 18th and 19th century, there were many important events, inventions, and inventors. In England at about 1805, William Strutt had invented at warm air furnace that included a riveted wrought iron air chamber that is encased with bricks.The design had a couple inches of space between the brick and iron chamber allows air to circulate. A large space on the outside is split horizontally on two sections, the lower for cool air and the upper for heated air. Cool air moves from the lower chamber through the openings and moved out through the upper openings into the heated air c hamber. As well as ducts were fed into rooms in which heated air is blown out of them. His hot air furnaces were referred to as cockle, belper, or derby stoves.December of 1815, Marquis de Chabannes obtained a patent for a method of conducting air, and regulating the temperatures in houses or buildings. Hot air systems were introduced in the U. S. before 1820. The fist building to be centrally heated was the Massachusetts Medical College in 1816. In 1831, Angier Perkins realized the drawbacks of bulky heating systems. So he designed a high pressure hot water system using a small diameter, thick walled wrought iron pipe that he patented. His system heated water in pipe coils placed in a furnace, then circulated hot water to coils of pipe in the rooms to be heated.In 1833, Eliphalet Knott invented the base burners for stoves, and in 1836, Isaac Orr invented the air tight stove so that there would be no heat loss. Joseph Nason and James Walworth introduced the Perkins method of high pr essure hot water heating system in the U. S†¦ But in that same year of 1842, the method was not used. The use of hot water systems had been limited till 1880’s when that had surprisingly become popular. Steam heating for residents had rapidly declined and hot water became the dominant method especially in the eastern part of the United States.Joseph and James installed steam systems afterward, using small diameter wrought iron pipes. They installed numerous amounts of steam systems in large buildings, including the White House and the Capitol building. In 1846, James and Nason installed the first fan type system for the United States Customs House in Boston. Later in 1849, F. P. Oliver had invented a stove with thermostatic draft control. By 1851, catalogs started to list cast iron registers, which are often 12-by-24-inch grills covering a large air-intake tube. Outflow vents vary in size depending on the room.A common size is 10 by 12 inches for most living spaces, avai lable in black, white, finished, gold, bronze, or just with nickel plating. They would package them with straw in a wooden crate. Packing was expensive. Stephen Gold was a Connecticut stove maker who began experimenting. The steam heating systems seemed too complicated and unsafe, but furnaces had seemed completely uncomplicated and very safe. Many people were uncomfortable in building heated by air because they had seamed scorched. Gold had overcome these issues and was granted a patent for improvement in warming houses by steam.Gold’s system was unique at the time. Large steam systems used coils or rows of pipe to heat rooms, while Gold used the first radiator, a device consisting of two dimpled iron sheets that were riveted together at dimples. The edges were rolled over with a piece of cord as a gasket, which is a rubber seal. Gold’s radiator came to be called â€Å"the mattress radiator† due to the way it looked, in 1854. In the same year, Gold invented a b oiler which was made of wrought iron and included a draft regulator along with a water valve.This system was later manufactured by Connecticut Steam Heating Company. Radiators date to 1863. Joseph Nason and a new face of Robert Briggs patented a new design including vertical wrought iron tubes screwed into a cast iron base. The golden age for warm air furnaces was after the Civil War. In 1869 a shoemaker by the name of Benjamin F. Sturtevant patented a combination fan and heat exchanger for two purposes: 1) for cooling 2) for heating. He established a company to manufacture and sell fans and heating systems. Here is a story that took place in 1873.Professor Warren Johnson taught at a school in Wisconsin where the only way to change the temperature was to run down to the janitor and have him turn the valves of air to change it to either warm or cool. Johnson developed an electric annunciator, which is electronic signaling device, system that was used to signal the janitor when heatin g need to be adjusted. In 1885, he created and patented a thermostat that relied on compressed air to operate the valves. He later established the Johnson Electric Service Company to manufacture and in install his systems. By 1874, Nelson Bundy invented the most popular cast iron radiator.In 1886, Albert Butz patented a thermostat that controlled damp drafts. The thermostat was electric, using battery to activate a spring loaded motor. In the 1890’s, the heating systems were quite sophisticated. Some included thermostatic and zone control, which is a forced air system. All of the early inventions of forced air systems had concerned themselves with large buildings. These combinations of the 1890’s of a fan and a heater were referred to as the plenum or the hot blast systems. In 1895, Charles Foster patented a damper type register. In 1899, Novelty Manufacturing Company was the first to make the steel register.The most successful hot blast system was the Vento sectional cast iron surface invented by John Spear in 1903, which was manufactured by American Radiator Company. Professor Warren Johnson went to invent the humidistat to control the humidity of a home in 1905. In that same year, manufacturers were frightened and formed the Federal Furnace League to elevate warm air heating to the rightfully deserved position. In 1905-1908, Milton Fessler invented a residential oil burner so that residents could have their own house heated easily without stoking coal in a fireplace every hour.During 1912, residents and homeowners had to wake up early to stoke the coal in the fire and replace the coal with fresh coal. Guesswork and experience helped tell how much coal to use. The first electric coal stoker that was controlled by a thermostat was invented in 1912, and by 1920 electric coal stokers could be found by anyone. During WWI, there was a coal shortage and the government had to find a way to conserve energy gave a slight nudge to the automatic systems. Lawrence Soule improved his idea of Aerofin heating surfaces. This Aerofin idea used spirally wrapped copper sheets to produce a light weight eat exchanger, during the 1920’s. After WWI, Butz Thermoelectric Regulator Company had pushed the idea of oil burner controls and had met with the Honeywell Heating Specialties in 1927 to form the Minneapolis Honeywell Regulator Company, or know to us today as Honeywell Incorporated. The heating systems of the 19th century operated with a low pressure, only using one to two pipes and a boiler or steam engine for the steam source. This is pretty much the last of the 18th-19th century events and inventions. This last paragraph explains the inventions and events in the 20th century.There are four main different types of modern central heating, consisting of gas and oil burners, solid fuel central heating, radiators, and electric heating. Gas and oil burners can be chimneys because they use gas to and oil to burn the wood to make a fire, wh ich warms up the room. Solid fuel central heating systems provide hot water, warm water, or any kind of heated liquid. Radiators  are heat exchangers used to transfer thermal energy from one medium to another for the purpose of cooling and heating. They distribute the heat by natural air circulation.The process of electric heating involves electrical energy being converted to heat through an electrical appliance. Other ways to heat homes are wood stoves, forced air systems, and by radiant heat. We also use thermostats that just â€Å"change† the temperature of rooms by the push of a button, that we often just take advantage of it. Houses often had ducts that come from a furnace that go to each room and blow air when you change the temperature on the thermostat. Some houses have a large panel of widows instead of a wall and the suns radiation waves go through the window and transfer into radiant heat to warm out the house.Another system houses have is called the forced air s ystem. Air is pushed by fans into a furnace and when it comes out, there are more fans after the furnace to push the air down the ducts and into the vents which lead into the room. This leads up to the year of 2013. So as it’s obvious, central heating has come a long way and improved much over the years. Many are impressed by this complicated technology and impressed by the intricate designs and inventions over the years. As spoiled people with high expectations of high quality technology, we have taken advantage of the heating systems.We just â€Å"turn on the heat† or â€Å"turn on the AC† and not even thinking about what has had to happen for this technology to come up to where it is. Heating is very important because without it we would not exist. We would freeze to death, literally. We owe a lot of thanks to all the inventors way back then who made this invention a lifestyle and a luxury. Heating has advanced so tremendously, from the campfire in a cave to something so silent so unnoticeable in life, from the hypocausts to the furnace, from the freestanding stoves to the chimneys.When we use heat or use a thermostat, we don’t tend to think about how heat has progressed. We think about the necessity of warmth, and how we are going to â€Å"freeze to death. † This paper and research has made me more aware of what happened for society to get heat, and has made me appreciate what I have. Fifty-four percent of the energy used in the average home is for heating and cooling rooms, and there are 114,199,622 households in the US as of the 2010 census. That’s a lot of energy used! The most simplistic way to put it is that we take advantage of things we have every day. I am thankful for heat, are you?

Text Organization Guide for English Learners

Text Organization Guide for English Learners Text organization refers to how a text is organized to help readers follow and understand the information presented. There are a number of standard forms that help text organization when writing. This text organization guide will help you logically guide your readers through your text. Text Organization: Referring to Ideas Already Presented Pronouns and determiners are used to refer to ideas, points or opinions that you have previously introduced, or will immediately introduce. Here is a quick review of pronouns and determiners with examples. Pronouns Remember that ideas, opinions, and arguments are considered objects in English which take object pronouns. it / it / its - singularthey / them / their - plural Examples: Its importance can not be underestimated.It now becomes clear that their role in production is vital.The government has given it ample consideration but rejected its validity. Determiners this / that - singularthese / those - plural This is key: Children need to be encouraged in order to succeed.Jefferson referred to those as unnecessary complications. Make sure that pronouns and determiners are clearly defined either before, or immediately after their introduction in order to avoid confusion. Examples: The need for economic growth is vital to any society. Without it, societies become defensive and ... (it refers to need for economic growth)These are vital for any job: interest, skills, manners... (these refers to interest, skills, manners) Text Organization: Providing Additional Information A number of forms are used to provide additional information in text organization. These forms are used at the beginning of a sentence to link text to the previous sentence: In addition to X, ...As well as X, ... Examples: In addition to these resources, we will require a further investment of ...As well as his difficulties in childhood, his continuing poverty as a young adult caused many problems. These phrases can be used in the middle of a sentence or a phrase to provide additional information in your text organization: alsoas well as Examples: Our commitment to the cause, as well as our financial resources, will make this possible.There was also time considerations to take into account. Sentence Structure: Not only...but also The sentence structure Not only clause, but also clause is also used to provide additional information and emphasize the later point in your argument: Examples: Not only does he bring experience and expertise to the company, but he also has an outstanding reputation.Not only are the students improving scores, but they are also having more fun. NOTE: Remember that sentences beginning with Not only ... use inverted structure (Not only do they do...) Text Organization: Introducing a Number of Points Its common to use phrases to signify the fact that you will be making different points in your text. The simplest way to indicate that you will be touching on a number of different points is to use sequencers. The appearance of sequencers indicates that there are points to follow or that precede your sentence. For more information on sequencers, continue on to the section on sequencing your ideas for text organization. There are also some set phrases that point to the fact that there are a number of points to follow. Here are the most common: There are a number of ways / means / manners ...The first point to make is ...Lets begin with the assumption that / the idea that / the fact that ... Examples: There are a number of ways we can approach this problem. First, ...Lets begin with the assumption that all of our courses are necessary for our students. Other phrases are used to indicate that one phrase is related to another in an additional sense. These phrases are common in text organization: For one thing ...and another thing / and for another ...besides that ...and besides Examples: For one thing he doesnt even believe what hes saying...., and another thing is that our resources cant begin to meet the demand. Text Organization: Contrasting Information There are a number of ways to contrast information in text organization. In most cases, two clauses are used: one with the most important information, as well as a clause introduced with a word or phrase showing contrast. The most common of these are although, though, even though, but, yet and despite, in spite of. Although, Even Though, Though Notice how though, even though or although show a situation which is contrary to the main clause to express conflicting information. Even though, though and although are synonymous. Use a comma after beginning a sentence with although, even though, though. No comma is required if you finish the sentence with although, even though, though. Examples: Even though it was expensive, he bought the car.Though he loves doughnuts, he has given them up for his diet.Although his course was difficult, he passed with the highest marks. Whereas, While Whereas and while show clauses in direct opposition to each other. Notice that you should always use a comma with whereas and while. Examples: Whereas you have lots of time to do your homework, I have very little time indeed.Mary is rich, while I am poor. Whereas, While But and yet provide contrary information that is often unexpected. Notice that you should always use a comma with but and yet. Examples: He spends a lot of time on his computer, yet his grades are very high.The research pointed to a specific cause, but the results painted a very different picture. Text Organization: Showing Logical Connections and Relations Logical consequences and results are shown by beginning sentences with linking language indicating a connection to the previous sentence (or sentences). The most common of these include as a result, accordingly, thus, hence, consequently. Examples: As a result, all funding will be suspended until further review.Consequently, the most important elements combine to provide a rich tapestry effect. Text Organization: Sequencing Your Ideas In order to help your audience understand, you need to link ideas together in your text organization. One of the most important ways to link ideas is to sequence them. Sequencing refers to the order in which events happened. These are some of the most common ways to sequence in writing: Beginning: Firstly,First of all,To start off with,Initially, Examples: Firstly, I began my education in London.First of all, I opened the cupboard.To start off with, we decided our destination was New York.Initially, I thought it was a bad idea, ... Continuing: Then,After that,Next,As soon as / When full clause,... but thenImmediately, Examples: Then, I started to get worried.After that, we knew that there would be no problem!Next, we decided on our strategy.As soon as we arrived, we unpacked our bags.We were sure everything was ready, but then we discovered some unexpected problems.Immediately, I telephoned my friend Tom. Interruptions / New Elements to the Story: Suddenly,Unexpectedly, Examples: Suddenly, a child burst into the room with a note for Ms. Smith.Unexpectedly, the people in the room didnt agree with the mayor. Events Occurring at the Same Time While / As full clauseDuring noun (noun clause) Examples: While we were getting ready for the trip, Jennifer was making the reservations at the travel agents.During the meeting, Jack came over and asked me a few questions. Ending: Finally,In the end,Eventually,Lastly, Examples: Finally, I flew to London for my meeting with Jack.In the end, he decided to postpone the project.Eventually, we became tired and returned home.Lastly, we felt we had had enough and went home.

Caligula essays

Caligula essays Caligula has been known to history as a colorful emperor. He is the youngest son of Germanicus Ceaser and the grandnephew of Tiberius. Caligula as a child was said to have been very ill with a high fever that probably affected his mind. That would explain all the strange things that he did throughout his life. Gaius was given the name Caligula (Latin for little boot) in the military camps where he spent some of his early life. He succeeded his granduncle Tiberius in the year 37. Caligula was very popular with the army at first since he had served himself. Unlike Tiberius, Caligula was not concerned with having a surplus in the Roman treasury. Soon after he came to power, he began to throw lavish festivals and gladiator games. The people of Rome knew that he was depleting the treasury, and quickly became unpopular. He soon answered them with acts of tyranny and began to have people executed at whim. He banished or murdered most of his own relatives. Caligula committed incest with two of his three sisters. His retreat is to Capri where he indulges himself in immoral acts In 37, Caligula becomes ill, and tells all that he is not really ill, but is metamorphasizing into a god. He then forces the Senate to deify himself and his three sisters. He also forces the Sensate to make his horse a Senator on the grounds that it is Alexander The Greats horse reincarnated. This all becomes too much for the people of Rome. The leader of the Praetorian Guard leads a revolt and Caligula is assassinated on January 24, 41. ...

3D Printing for the Built Environment-Free-Samples for Students

3D printing is the process of manufacturing an object in three dimension formations with material layer by layer. 3D printing is one of the additive layer fabrication processes, this technology uses a computer-based system to make a 3D model of the object and manufacture it by adding a layer at a time. This technology has enhanced and significantly upgraded into a great instrument for various fields. Merging various fields in single product formed 3D printer as it involves design, electronics, manufacturing, materials and business. 3D printing is known as additive manufacturing, as it is not like subtractive manufacturing and it adds material with lot of layers instead of removing material (Hager, Golonka and Putanowicz, 2016). This is beneficial for many fields such as researchers, manufacturers, designers, engineers and scientists. The 3D printing technology is revolutionising the procedure of manufacturing in various industries. It entirely modifies not only the manufacturing fiel d, but also entire life of people in the future as 3D printer makes feasible to complete model in a single process. 3D printing is an advancement of printing technologies which can manufacture or reproduce elegant structures in one piece. This technology offers direct manufacturing as through a printer, physical product can be generated directly by inputting a design from an idea. 3D printing is an innovative technology, it started in the 80’s and named as â€Å"rapid prototyping†. Today, 3D printers offer to manufacture a physical object from digital model as per the imagination. In order to use 3D printer, firstly preparation is mandatory before printing, like designing a 3D file of the object that has to be printed. To design 3D model or file there are many ways such as through CAD software, websites like Blender and Google SketchUp or it can be simply downloaded from online marketplace for pre made designed models (Kellens, et. al., 2017). When the 3D model is ready for printing then the printing process has to be done. For printing process, initially material has to be decided which would be required for the object. 3D printing provides vast variety of materials such as plastics, resins, sand, ceramics, metals, textiles, biomaterials, glass, food and also lunar dust (Peng, 2016). After deciding the materials for manufacturing and finishing of the object for the accurate result of design, the object has to be printed and if it has not been sanded, lacquered or painted to finish it as deliberated then usually it cannot be directly used or delivered. Printin g methods depend on material selected for the project. Printing techniques of each material are described; if plastic or alumide has to be used during manufacturing then fused deposition modelling technology (FDM) and SLS technology would be best suitable. FDM is the most frequently used printing technique because of the number of printers accessible in the market. In this technique the material is being melted and emitted with the help of a nozzle by each layer at a time to 3D print the object. Thickness of the layer is influenced by the quality of 3D print (Sculpteo, 2018). As compared to other 3D printing technologies, FDM is an affordable 3D printing process. SLS technology is a laser sintering 3D printing technique which includes fabrication of an item by melting layers of powder collectively to manufacture an object. If the materials are resin or wax during the additive manufacturing then there are four methods of 3D printing such as Stereo lithography (SLA), Digital light processing (DLP), Continuous liquid interface production (CLIP) and Multi jet printers. A tank is used of remediable photopolymer resin in SLA method. The build plate goes down and where UV laser creates cross section layer by layer then the liquid polymer is exposed to light. DLP method is similar as the SLA method, the difference is that in DLP method a safelight is used instead of UV laser to cure the photopolymer resin (Sculpteo, 2018). DLP method can be used for silver and brass 3D printing. CLIP method is used with a continuous sequence of UV images which are produced by a digital light projector, with the help of an oxygen permeable, UV transparent window under a liquid resin bath. Multi Jet printers are similar to SLA method, in this method UV light is used by poly jet and multi jet 3D printing techniques to link a phot opolymer. A printer jet pours tiny droplets of the photopolymer in the shape of the first layer and not scan laser to cure layers. When metal has to be used as material, then the methods would be DLP, Direct metal laser sintering (DMLS) and Electron beam melting (EBM). DLP can be used for silver and brass 3D prints. Primarily a wax model is 3D printed then lost was casting technique is used as before the wax is melted the pattern has to be made around it to create the object. In DMLS method laser is used as primary source to sinter metal powder through laser cross section layer by layer of the object (Sculpteo, 2018). In EBM method laser is not used during 3D print, instead of laser and electron beam is used to 3D print the metal. This electron beam melts the metal powder layer by layer and has ability of full melting of the metal powder. When multicolour is required during the 3D printing, then the methods used are Binder jetting, Selective deposition lamination (SDL) and Triple jetting technology (Poly jet). Binder jetting is very popular and useful as it provides the facility of producing detailed 3D prints with colour. To apply a layer of powder on the build platform, the automated roller is used. Liquid binder and colour can also be applied to create a cross section of the product. SDL method is processed with the help of paper. In this process layers of adhesive coated paper are stuck together with the support of high temperature roller and then slash with a laser cutter to give the appropriate shape (Fosso, 2017). Triple jetting technology includes printing with the three materials and can also use three colours. 3D printing is experiencing a boom in recent years. This technology is also known as additive manufacturer and helps to design and manufacture products faster than ever before. Hence, it is becoming more potential even if we consider environmental issues. 3D printing is friendly for environment by supportable material. If we think about sustainability then the important part is material used for 3D printing (Chen, 2016). In the last years, there have been some cases where development of 3D printer materials from recycled plastic has been practiced. According to Joshua Pear the plastic fibre from milk jugs is energy efficient. 3D printing is turning waste into fashion as this technology is not only helpful in reducing waste. Whereas, it also offers variety of ways for reuse the waste for the fashion industry. For example, the sports brand Adidas has printed shoe, which has a 3D printed midsole manufactured from recycled fishing nets. 3D printing uses a lot of energy. 3D printers are utilizing lasers or heat 50 to 100 times more electricity than production from traditional techniques to manufacture the same object of the equal weight. However, it has important impact on environment as in many areas electricity has been generated from fossil fuel sources (Liu, et. al., 2016). Less material is being used in 3D printing technology as compared to traditional manufacturing methods. 3D printing methods offers to melt, fuse, bind and sinter the amount of plastic, metal and ceramic. Whereas, in subtractive manufacturing usually cutting has to be done of excess material so the additive manufacturing is very different from the subtractive manufacturing. As energy has not been used to produce extra material and also to remove it during subtractive method has to be done. Hence, it uses less energy as compared to other methods. 3D printing is beneficial for environment as it has the ability to print objects at any place like at store or at home and this reduces the need to transport the objects manufactured. Hence, helpful in lowering the emissions caused with the transportation. 3D printed products are usually up to 50 per cent lighter than the products manufactured through standard techniques (Pirjan and Petrosanu, 2013). Hence, during transportation of the 3D printed products, less energy would be required. Whereas, the transportation is very less of the overall environmental impacts because when a product has to be shipped from thousands of miles away in any other country. 3D printed objects are usually manufactured of thermoplastic, which is not the greenest material and cannot be frequently recycled. Thermoplastic can be recycled by several machines in the market like the material which is from unsuccessful prototypes for use in 3D printers (Mendoza, 2015). Whereas, the more this recycled plastic is being recycled it becomes more delicate which tend users to become reluctant to try it. The industry is trying and working on improving their recycling technologies. 3D printing is environmentally-friendly as it prevents to use traditional petroleum based materials and includes the use biodegradable and renewable plant based sources. The two major plastics used in additive manufacturing come from corn (Rogers, et. al., 2016). Poly lactic acid creates little waste as it is biodegradable, renewable and nontoxic. In this industry because of these reasons this choice is on priority. This industry asks their designers to make lighter weight products. More time would be consumed for making something big. So, they line up the incentive structures of the economies and this would be helpful in meeting environmental priorities. 3D printing offers to manufacture the light weight and strong complex shapes very fast. This technique helps in manufacturing cars and wind turbines and when these products are made with lighter weight parts then they can be helpful in saving energy. 3D printing also has positive impact socially than environmental (Silva Barros, 2017). As 3D printing can be used at any place for printing objects, then this technique should be used in developing countries that are not connected from global supply chains. Additive manufacturing can efficiently employ raw materials and their functionality. In a powder based process, nonconsolidated raw materials are used such as in powder bed fusion that can be reused that would help in diminishing material waste (Boon and Van, 2017). Optimisation in the design of the object has been enabled by free form fabrication of the additive manufacturing. The optimal design will help in reduction of materials, energy, fuel, or natural resources in the product manufacturing.   When huge amounts of energy are wasted like in moulding or casting, then the additive manufacturing can change the process and can also save resources utilised on the fabrication of tooling during production. 3D printing is revolutionizing every field. This technique is beneficial for environment in many ways such as, new body parts can be printed and working ovaries for mice can be created. Biologists made infertile mice fertile again by providing them 3D printed ovaries. Hence, it can be said that this technique is helpful in saving the world (Mohr and Khan, 2015). This technique is helpful in predicting natural disasters as 3D geospatial modelling is easy to create, carry and transfer environmental safety messages, 3D landscapes has been best way of communication for geoscientists by satellites designed for disaster response. With the help of 3D printing, scientists can provide an understanding to people regarding landscape and the risk (Insight, 2013). This help in taking prior and effective actions for safety. All over the globe these printed models are being used for the safety purpose, these address critical problems such as cliff erosion, volcanic eruption and wildfires. 3D printi ng technique offers to create a bamboo bike by using natural resources like hemp and resin (Baumann and Roller, 2017). This bike has been created by using sustainably sourced material, holding bamboo rods together by tubular joining pieces called lugs. Lugs have been created by bio fibre and a plant based resin glue. When bamboo bicycle is created by using 3D printing then it has been analysed that lugs have been created from carbon fibre filament, carbon fibre is recyclable.      3D printing can be done on demand, as parts can be manufactured when they are required by producing on demand. This simply means instead of manufacturing products in bulk, now with the help of 3D printing production can be done when the objects are needed. This is beneficial in saving storage (Surange and Gharat, 2016). The less manufacturing of stock allows putting the less capital, on demand production is also beneficial because risk of unsold stock or wastage stock is less and also prevent from selling the stock on discount (Garcia, Claver and Sebastian, 2017). 3D printing lower the carbon dioxide footprint, other manufacturing techniques causes the emission of carbon dioxide because most of the machines use fuel for their operation. The carbon dioxide causes air pollution and global warming. According to the research done by an aerospace and defence research organisation on the environmental impacts of additive printing, it was found that along with the fact that this technique s ave usage of energy and reduce the carbon dioxide emission during transportation, 3D printing also makes lighter aircraft components, almost 40% less carbon dioxide has been used during the production process of these kind of printed parts. It has been concluded from the above report that 3D printing technology has positive impact on the environment. 3D printing is also known as additive manufacturing and we have discussed the process of using 3D printing and also discussed about the materials used in this technique. There are different methods of 3D printing according to various materials. We have discussed the advantages and limitations of this technique. 3D printing is having a tremendous impact on industries such as aerospace and automotive to healthcare. This technique is turning waste into fashion, as it is utilizing waste in fashion industry. Huge amount of electricity and energy is being saved in this technique as compared to other techniques. 3D printing prevents the carbon dioxide emission. It is beneficial for environment as it prevents to use petroleum based materials and tends to use biodegradable and renewable sources. With the help of 3D printing technique the transportation has been reduced as it can be used anywhere and this technique offers to manufacture lighter weight products. This technique helps in knowing the disasters previously so that prior safety actions could be taken. 3D printing is an additive manufacturing which is beneficial for environment. Baumann, F.W. and Roller, D., 2017. Additive Manufacturing, Cloud-Based 3D Printing and Associated Services—Overview.  Journal of Manufacturing and Materials Processing,  1(2), p.15. Boon, W. and Van Wee, B., 2017. Influence of 3D printing on transport: a theory and experts judgment based conceptual model.  Transport Reviews, pp.1-20. Chen, Z., 2016. Research on the impact of 3D printing on the international supply chain.  Advances in Materials Science and Engineering,  2016. da Silva Barros, K., 2017.  Identification of the environmental impacts contributors related to the use of Additive Manufacturing technologies  (Doctoral dissertation, Università © Grenoble Alpes). Fosso Wamba, S., 2017. 3D Printing and Supply Chain Management: A Literature Review and Research Agenda. In  5th International Conference on Mechanical Engineering (Meche), September  (Vol. 30). Garcà ­a-Domà ­nguez, A., Claver, J. and Sebastià ¡n, M.A., 2017. Study for the selection of design software for 3D printing topological optimization.  Procedia Manufacturing,  13, pp.903-909. Hager, I., Golonka, A. and Putanowicz, R., 2016. 3D printing of buildings and building components as the future of sustainable construction?.  Procedia Engineering,  151, pp.292-299. Insights, M.M., 2013. Layer-by-Layer: Opportunities in 3D printing Technology trends, growth drivers and the emergence of innovative applications in 3D printing. Kellens, K., Baumers, M., Gutowski, T.G., Flanagan, W., Lifset, R. and Duflou, J.R., 2017. Environmental dimensions of additive manufacturing: Mapping application domains and their environmental implications.  Journal of Industrial Ecology,  21(S1). Liu, Z., Jiang, Q., Zhang, Y., Li, T. and Zhang, H.C., 2016, June. Sustainability of 3D Printing: A Critical Review and Recommendations. In  ASME 2016 11th International Manufacturing Science and Engineering Conference  (pp. V002T05A004-V002T05A004). American Society of Mechanical Engineers. Mendoza, A.J., 2015. Legal and Social Implications of the 3D Printing Revolution. Mohr, S. and Khan, O., 2015. 3D Printing and Supply chains of the Future.  Innovations and Strategies for Logistics and Supply Chains, pp.147-174. Peng, T., 2016. Analysis of energy utilization in 3d printing processes.  Procedia CIRP,  40, pp.62-67. Pà ®rjan, A. and Petrosanu, D.M., 2013. The impact of 3D printing technology on the society and economy.  Journal of Information Systems & Operations Management, p.1. Rogers, H., Baricz, N. and Pawar, K.S., 2016. 3D printing services: classification, supply chain implications and research agenda.  International Journal of Physical Distribution & Logistics Management,  46(10), pp.886-907. Sculpteo, 2018. 3D Printers and 3D Printing: Technologies, Processes and Techniques [Online]. Accessed from: https://www.sculpteo.com/en/3d-printing/3d-printing-technologies/ [2 nd April 2018]. Surange, V.G. and Gharat, P.V., 2016. 3D Printing Process Using Fused Deposition Modelling (FDM).  International Research Journal of Engineering and Technology (IRJET),  3(03).

Literature Research Paper Example | Topics and Well Written Essays - 500 words

Literature - Research Paper Example He suggests that Allende is plagiarizing Garcia’s work other than being creative. Beginning with the starting few sentences of the house of the spirits, he acknowledges that they do belong to Garcia’s book (Antoni 16). The tone and technique used in Allende’s starting passage is a like to that of Garcia. This he refers to as â€Å"the language of the magic realism†. This he suggests is because as Allende tries to realize her own language in her writing, she ends up using Garcia’s already established language. It is ironical to, also note that, from his analysis, the last few sentences from Garcia’s book are from Allende’s book. As Antoni compares the two novels, it is revealed further that though Allende is attempting to make a difference between her novel and that of Garcia, there are some parts that do not make a big difference (Antoni 19). For instance, she stipulates in her first sentence that the writing of the novel is 50 years after the occurrence of the events in the novel. Garcia, on the other hand, writes that Buendias were prophetically written by Melquiades a century before the events. This implies that Garcia’s book is in the jurisdiction of the mythological time whereas Allende’s book is more of ancient than legendary (Antoni 20). Antoni further gives instances in the two novels that prove of Allende’s alleged plagiarism. In one instance, he views the characteristics of Tio Marcos found in Allende’s novel being obtained from Garcia’s Melquiades. This is because the two characters die, and are resurrected, they are adventurers, they bear the magical books, an d are astronomers among other similar characteristics they acquire. This implies that Allende’s novel fetches so much information from Garcia’s novel (Antoni 25). An instance where Allende is imitating Garcia knowingly iswhere; Clara insists that names should not be repeated in the